Substrate Games

Substrate Games is an independent software development studio that builds educational software, has developed a game-based learning app for students learning organic chemistry. It is a spinout company from Iowa State University.

Substrate Games is reimagining how traditionally challenging health-focused science concepts are learned and taught.

Substrate Games was founded in 2015 by Will Schneller & Eve Wurtele and is based in Des Moines, Iowa.


Substrate Games is building a platform based on the mechanics of nature to make challenging science concepts intuitive, engaging, and enjoyable. The company's ultimate goal is to use this platform to create new experiences that span from gaming to education.


Substrate Games, in May 2019, has been awarded a competitive SBIR Phase II grant from the National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) Division for Research Capacity Building (DRCB) totaling $1,491,415. The company has also raised funding from Iowa Dept of Economic Development & National Science Foundation.



  • Year founded: 2015
  • Funding Info: $2M in 3 Funding Rounds (Last Funding Type: Grant)
  • Yearly Revenue: NA
  • Employee Size: 2-10
  • Business Valuation: NA
  • City/Town: Des Moines
  • State: Iowa
  • Country: United States
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