Plume is a comprehensive, virtual care provider built by and for the health care needs of the transgender community.

Plume's mission is to create deeply affirming direct-to-consumer pharmaceutical services for the trans and broader queer community.

Plume was co-founded in 2019 by Matthew Wetschler and Jerrica Kirkley. The company is headquartered in Denver, Colorado.

Plume is the only digital-health company entirely dedicated to services for trans and gender diverse individuals and their families and is uncompromisingly focused on providing the best care experience available.

Plume offers a 24/7 access to gender-affirming care, personal consultations, lab testing, facilitated support groups, medical letters of support for surgery and name and gender marker changes, and home delivery of prescriptions and gender-affirming medication as medically appropriate.

Plume is available to over 90% of the trans population across the United States.

Plume is backed by Craft Ventures, General Catalyst, Slow Ventures, Transformation Capital, Town Hall Ventures, and others. The company raised $24M in a Series B round on Aug 23, 2022. This brings Plume's total funding to $38M to date.