Plume is a comprehensive, virtual care provider built by and for the health care needs of the transgender community.

Plume's mission is to create deeply affirming direct-to-consumer pharmaceutical services for the trans and broader queer community.

Plume was co-founded in 2019 by Matthew Wetschler and Jerrica Kirkley. The company is headquartered in Denver, Colorado.


Plume is the only digital-health company entirely dedicated to services for trans and gender diverse individuals and their families and is uncompromisingly focused on providing the best care experience available.


Plume offers a 24/7 access to gender-affirming care, personal consultations, lab testing, facilitated support groups, medical letters of support for surgery and name and gender marker changes, and home delivery of prescriptions and gender-affirming medication as medically appropriate.


Plume is available to over 90% of the trans population across the United States.


Plume is backed by Craft Ventures, General Catalyst, Slow Ventures, Transformation Capital, Town Hall Ventures, and others. The company raised $24M in a Series B round on Aug 23, 2022. This brings Plume's total funding to $38M to date.



  • Year founded: 2019
  • Funding Info: $38M over 2 Rounds (Latest Funding Type: Series B)
  • Yearly Revenue: NA
  • Employee Size: 51-200
  • Business Valuation: NA
  • City/Town: Denver
  • State: Colorado
  • Country: United States
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